ADC研究员/首席研究员 ADC Scientist / Principal ADC Scientist(J12465)
岗位信息
| 招聘单位 | 凯莱英 |
|---|---|
| 工作地点 | 上海市 |
| 官方更新时间 | 2025-09-27T20:32:24 |
职位描述
Develop conjugation (cysteine/lysine/enzymatic) for ADCs; optimize parameters (kinetics, stoichiometry) for DAR/purity/stability;
Develop purification (CEX, AEX, HIC, AC) for crude ADC;
Scale-up conjugation (bench to 100L+); prepare tech transfer docs.
Support CMC on formulation, analytics & IND/BLA.
任职要求
PhD in Biochemistry/Chemical Biology 1 yr ADC experience, or 3 yrs ADC conjugation development.
Conjugation & Purification with ≥2 methods (e.g., cysteine, THIOMAB™, enzyme) & ≥2 purification (e.g., TFF, CEX, HIC)
Process Development with cGMP/ICH scale-up experience (DOE/QbD)
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