体外药理学副总监/总监(J18004)

职位描述

-Lead a small group to design, optimize, and validate of of novel therapeutic candidates.

-Utilize internal facilities or manage external CRO in supporting of preclinical PCC and IND enabling studies through clinical development

-Propose and lead new projects in both autoimmune and oncology fields

-Oversee project prioritization, resource allocation, and timelines to ensure the timely delivery of high-quality data

-Serves as the functional representative to work with teams from other disciplines

-Present research findings at internal and external project meetings in both Chinese and English

-Review research documents, including study reports, regulatory filings (e.g., IND), and scientific publications

-Lab and equipment management

任职要求

-Ph.D. in Immunology, Cell Biology, Molecular Biology, Biochemistry, or a related discipline is required

-A 8+ years of job-related experience preferably in a biopharmaceutical R&D setting, with a strong focus on preclinical bioassay development is required

-PTL experience in supporting PCC and IND enabling studies is required.

-Proven records of in vitro cell based functional assay using various types of immune cells and tumor cells, and cell-based assay development is required, including but not limited to reporter assay, ELISA, BLI/SPR, flow cytometry, cell adhesion and migration, killing. T-cell/Treg/NK/basophil activation, T-cell cytotoxicity, cytokine profiling, ADCC, ADCP, CDC), GPCR signalling, epitope analysis.

-Experience in organoid culture, and mammalian tissue assay is preferred

-Excellent communication skills and problem-solving skills, with the ability to effectively collaborate in a fast-paced, cross-functional environment.

-Experience and knowledge in tumor immunology and Inflammatory diseases is a plus

-Strong publication and presentation record in relevant scientific fields is desired.

-Excellent written and communication in English